N-Acetylneuraminic acid attenuates hypercoagulation on high fat diet-induced hyperlipidemic rats
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چکیده
منابع مشابه
N-Acetylneuraminic acid attenuates hypercoagulation on high fat diet-induced hyperlipidemic rats
BACKGROUND AND OBJECTIVE N-Acetylneuraminic acid (Neu5Ac), a type of sialic acid, has close links with cholesterol metabolism and is often used as a biomarker in evaluating the risk of cardiovascular diseases. However, most studies on the health implications of Neu5Ac have focused on its effects on the nervous system, while its effects on cardiovascular risk factors have largely been unreported...
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N-Acetylneuraminic acid (Neu5Ac) is a biomarker of cardiometabolic diseases. In the present study, we tested the hypothesis that dietary Neu5Ac may improve cardiometabolic indices. A high fat diet (HFD) + Neu5Ac (50 or 400 mg/kg BW/day) was fed to rats and compared with HFD + simvastatin (10 mg/kg BW/day) or HFD alone for 12 weeks. Weights and serum biochemicals (lipid profile, oral glucose tol...
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ژورنال
عنوان ژورنال: Food & Nutrition Research
سال: 2015
ISSN: 1654-6628,1654-661X
DOI: 10.3402/fnr.v59.29046